Qilong Xu
Name: Qilong Xu
Affiliation:
Email: qxu@vetmed.lsu.edu
PROFESSIONAL EXPERIENCE
July 2006- present
Senior Postdoctoral Researcher Louisiana State University, Baton Rouge, LA
July 2004- June 2006
Postdoctoral Researcher Louisiana State University, Baton Rouge, LA
June 1999 to July 2000
Visiting Scholar University of Kentucky, Lexington, KY
July 1997 to June 1999
EDUCATION
August 2000-June 2004
Ph.D, University of Kentucky, Lexington, KY
Dissertation Title: Isolation and characterization of a second PROTEIN L-ISOASPARTYL METHYLTRANSFERASE gene in Arabidopsis*
*an interesting enzyme repairing damaged protein.
September 1994-July 1997
M.S., Shandong Agricultural University, Taian, Shandong, China
Thesis title: Establishment of an efficient tomato transformation system and generation of transgenic plants containing ToMV 54KD ORF.
September 1990-July 1994
B.S., Shandong Agricultural University, Taian, Shandong, China
AWARD AND HONORS
Ad Hoc Reviewer for the Journal of Biochemical and Biophysical Methods. 2007
First Place, Graduate Students’ Award for Excellence in Research (M.S.), 1997
First Class Scholarship for Undergraduates, 1990 to 1994
AFFILIATIONS
Member of American Society for Microbiology, 2006 to present
Member of American Society of Plant Biology, 2001 to 2004
PUBLICATIONS
1. Xu Q, McShan K, and Liang FT. 2008. Collective functioning from dual operators achieves maximum downregulation of the ospAB operon by Borrelia burgdorferi during mammalian infection. Submitted for publication.
2. Xu Q, Shi Y, McShan K, and Liang FT. 2008. Simultaneous expression of the virulence factors OspC, DbpA and DbpB in Borrelia burgdorferi cannot override the requirement for RpoS in murine infection. In revision.
3. Xu Q, McShan K, and Liang FT. 2008. Modification of Borrelia burgdorferi to overproduce OspA or VlsE alters its infectious behavior. In revision.
4. Xu Q, McShan K, and Liang FT. 2008. Essential protective role attributed to the surface lipoproteins of Borrelia burgdorferi against innate defences. Mol Microbiol 69(1) 15-29.*
*There is a commentary on this paper in the same issue.
5. Shi Y, Xu Q, McShan K, and Liang FT. 2008. Both decorin-binding proteins A and B are critical for the overall virulence of Borrelia burgdorferi. Infect Immun 76(3) 1239-1246.
6. Xu Q, McShan K, and Liang FT. 2008. Verification and dissection of the ospC operator by using flab promoter as a reporter in Borrelia burgdorferi. Microb Pathog 45: 70-78.
7. Dinkins RD, Majee SM, Nayak NR, Martin D, Xu Q, Belcastro MP, Houtz R, Beach CM, Downie AB. 2008. Changing transcriptional initiation sites and alternative 5'- and 3'-splice site selection of the first intron deploys the Arabidopsis Protein Isoaspartyl Methyltransferase2 variants to different subcellular compartments. Plant J 55(1): 1-13.
8. Xu Q, Seemanapalli SV, McShan K, and Liang FT. 2007. Increasing the interaction of Borrelia burgdorferi with host decorin significantly reduces 50% infectious dose but severely impairs spirochetal dissemination. Infect Immun 75(9) 272-4281.
9. Xu Q, Seemanapalli SV, Reif KE, Charles R. Brown and Liang FT. 2007. Increasing the recruitment of neutrophils to the site of infection dramatically attenuates Borrelia burgdorferi infectivity. J Immunol 178: 5109-5115.
10. Xu Q, Seemanapalli SV, McShan K, and Liang FT. 2007. Identification of an OspC operator critical for immune evasion of Borrelia burgdorferi. Mol Microbiol 64(1): 220-231.
11. Shi Y, Xu Q, Seemanapalli SV, McShan K, and Liang FT. 2006. The dbpBA locus of Borrelia burgdorferi is not essential for infection of mice. Infect Immun 74: 6509-6512.
12. Villa ST, Xu Q, Downie AB, Clarke SG Clarke. 2006. Arabidopsis protein repair L-isoaspartyl methyltransferases: predominant activities at lethal temperatures. Physiol Plantarum 128: 581-592.
13. Xu Q, Seemanapalli SV, McShan K, and Liang FT. 2006. Constitutive expression of outer surface protein C diminishes the ability of Borrelia burgdorferi to evade humoral immunity. Infect and Immun 74: 5177-5184.
14. Xu Q, Seemanapalli SV, Lomax L, McShan K, Li X, Fikrig E, and Liang FT. 2005. Association of linear plasmid 28-1 with an arthritic phenotype of Borrelia burgdorferi. Infect and Immun 73: 7208-7215.
15. Xu Q, Zhang D, Downie AB. 2005. Rapid and efficient sub-cloning DNA into plasmid vectors without dephosphorylation or gel eletrophoresis. Mol Biotechnol 29: 111-118
16. Xu Q, Belcastro MP, Villa ST, Dinkins RD, Clarke SG. Downie AB. 2004. A second PROTEIN L- ISOASPARTYL METHYLTRANSFERASE gene in Arabidopsis produces two transcripts whose products are sequestered in the nucleus. Plant Physiol 136: 2652-2664.
17. Downie AB, Dirk LMA, Xu Q, Drake J, Zhang D, Dutt M, Butterfield A, Geneve RR, Corum III JW, Lindstrom KJ and SnyderJC. 2004. A physical, enzymatic, and genetic characterization of perturbations in the seeds of the brown seed tomato mutants. J Exp Bot 55: 961-973.
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