Rahul Sharma
Name: Rahul Sharma
Affiliation: private
Email: rsharm4@lsu.edu
Post Doctoral Fellow (Since 25 March 2008): National hansen's Disease programe @ LSU SVM, Baton Rouge LA, USA 70803.
Project: Study molecular neuropathy during infection in the nerves by using functional genomics in Armadillo as a model for neuropathy.
Doctor of Philosophy (Biotechnology) 2008
Title: Analysis of genes involved in important metabolic pathways in Mycobacterium leprae using structural and functional genomic approaches
Supervisor: Dr. VM Katoch, MD, FNASc, FNA, FNAMS
Secretary, Department of Health Research (DHR), Govt. of India Place of work: Department of Microbiology & Molecular Biology, National JALMA Institute for Leprosy & Other Mycobacterial Diseases (ICMR) Tajganj Agra 282001- India
* Qualified CSIR-UGC NET (National Eligibility Test) 2001
* Qualified CSIR-UGC, NET & awarded JRF (Jounior Research Fellowship) 2002
Master of Science in Microbiology in year 2002
Dr. B.R. Ambedkar University, AGRA
Bachelor of Science in year 1999
Major: Chemistry, Zoology, Botany
University of Rajasthan, JAIPUR
PATENTS:
1. Expression of virulence factors of M.leprae in host during infection by functional genomic approaches. (Indian Patent Application No- 2012/DEL/2006)
2. Probes and primers for identification of mycobacterial proteins useful as potential drug targets. (Indian Patent Application No-884/DEL/2007)
3. Novel probes, primers and DNA Chip. (Indian Patent Application No-2071/DEL/2007)
RESEARCH PROJECTS COMPLETED:
1. Doctor of Philosophy (Biotechnology): 2008
Title: Analysis of genes involved in metabolic pathways in Mycobacterium leprae using structural and functional genomic approaches
M. Sc (Microbiology) Dissertations: 2002
(A) Title: Characterization of Mycobacterium bovis isolates by PCR-RFLP targeting 1.2 Kb r-RNA Gene Region Using Restriction Enzyme HhaI. From Department of Molecular Biology & Microbiology, Central JALMA Institute for Leprosy (ICMR), Agra, under the supervision of Dr. V.M. Katoch, Director, CJIL.
(B) Title: Studies on Radioimmunotargetting (RIT) in Experimental Animals (nude mice)”. From Nuclear Medicine Unit (NMU) of S.N. Medical College AGRA, under the supervision of Dr D.K. Hazra, Prof & Head, NMU, S.N. Medical College, Agra.
IMPORTANT PUBLICATIONS:
1. Rahul Sharma and VM Katoch (2006). Designing of oligonucleotides: Probes and Primers for diseases diagnosis, epidemiology and research in medicine. Journal of communicable Diseases; 38: 305-316
2. Mallika Lavania, Kiran Katoch, HB Singh, Ram Das, Anuj Kumar Gupta, Rahul Sharma, DS Chauhan, VD Sharma, P Sachan, S Sachan and VM Katoch (2007). Predominance of three copies of tandem repeats in rpoT gene of Mycobacterium leprae from Northern India. Infect Genet and Evol – 7(5): 627-631.
3. V.M. Katoch, Mallika Lavania, DS Chauhan, Rahul Sharma and Hirawati (2007). Advances in molecular biology of leprosy. Ind J Lepr 79: 151-166.
4. Mallika Lavania, Kiran Katoch, Vishwa Mohan Katoch, Anuj Kumar Gupta, Devendra Singh Chauhan, Rahul Sharma, Rashi Gandhi, Varsha Chauhan, Gurpreet Bansal, Pawan Sachan, Shailendra Sachan, V.S. Yadav, Rupendra Jadhav (2008). Detection of viable Mycobacterium leprae in soil samples: Insights into possible sources of transmission of leprosy. Infect Genet Evol. 2008 8(5):627-631
5. Mallika Lavania, Kiran Katoch, Rahul Sharma, Pragya Sharma, Ram Das, Anuj Kumar Gupta, Devendra Singh Chauhan. Analysis of potential short tandem repeats for molecular typing of Mycobacterium leprae strains from Northern India: Ind J Med Res (submitted).
6. Rahul Sharma, M Lavania, K Katoch, DS Chauhan, AK Gupta, UD Gupta, VS Yadav and VM Katoch. Development and Evaluation of Real-Time RT-PCR Assay for Quantitative Estimation of Viable Mycobacterium leprae in Clinical Samples: Indian J Lepr 2008, 80: 315-321.
7. Rahul Sharma, Mallika Lavania, DS Chauhan, Kiran Katoch, Amresh, Pramod, Rakhi, Richa and VM Katoch. A metabolic gene (accA3) of M. leprae as potential marker for leprosy reactions. Indian J Lepr (Submitted)
Active participant in other Project:
v Detection of Hypermethylation in P16 gene in high risk individuals for lung cancer.
v A survey of the prevalence of anti-TB drug resistance in Agra and Kanpur Districts.
v Genomic diversity of leprosy bacillus and expression of its genes in the host.
v Comparative and functional genomic approaches for the identification and characterization of genes responsible for multidrug resistance in M.tuberculosis.
v Development of probes and primers for detection of mutations by Real Time PCR.
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